Sibutramine

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Sibutramine 15mg , formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. Sibutramine For Sale

Uses Of Sibutramine:

• Psychiatric conditions as bulimia nervosa, anorexia nervosa, serious depression or pre-existing mania
• Patients with a history of or a predisposition to drug or alcohol abuse
• Hypersensitivity to the drug or any of the inactive ingredients
• Patients below 18 and above 65 years of age
• History of peripheral arterial disease
• Hypertension that is not sufficiently controlled (e.g., >145/90 mmHg), caution in controlled hypertension
• Existing pulmonary hypertension
• Existing damage on heart valves, coronary heart disease, congestive heart failure, serious arrhythmias, previous myocardial infarction
• A history of coronary artery disease (e.g., angina, history of myocardial infarction), congestive heart failure, tachycardia, peripheral arterial
• Occlusive disease, arrhythmia or cerebrovascular disease (stroke or transient ischemic attack (TIA))
• Hyperthyroidism (overactive thyroid gland)
• Closed-angle glaucoma
• Seizure disorders
• Enlargement of the prostate gland with urinary retention (relative contraindication)
• Pheochromocytoma
• Pregnant and lactating women (relative contraindication).

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Sibutramine Effects

The aim of the study was to assess the effectiveness and safety of long-term sibutramine therapy in routine clinical practice. sibutramine pills for sale

Methods: In total, 98,774 patients (82.3% women, 17.7% men) from 142 cities of the Russian Federation were enrolled in the PRIMAVERA program. The mean age of the patients was 39.39 ± 10.38 years, the mean body weight was 99.1 ± 14.28 kg, and the mean BMI was 35.7 ± 4.41 kg/m2. The duration of the sibutramine therapy was determined by physicians: 59.3% of patients took the drug for 6 months, the treatment course of 37.7% of patients was 12 months, and 3% of patients had treatment for 3 months.

Results: The BMI reduction correlated with the treatment duration: 3.4 ± 1.53 kg/m2 after 3 months of therapy, 5.4 ± 2.22 kg/m2 after 6 months, and 7.2 ± 3.07 kg/m2 after 12 months. The body weight reduction after 3, 6 and 12 months of treatment was 9.5%, 15.1%, and 19.7%, respectively. The body weight loss associated with sibutramine treatment was accompanied by a slight decrease in blood pressure and did not lead to any significant increases of the heart rate.